Endothelial Protein C Receptor Could Contribute to Experimental Malaria-Associated Acute Respiratory Distress Syndrome
L. S. Ortolan, M. K. Sercundes, G. C. Moura, T. C. Quirino, D. Debone, D. S. Costa, O. Murillo, C. R. F. Marinho, S. Epiphanio
This study investigates the role of endothelial protein C receptor (EPCR) in malaria-associated acute respiratory distress syndrome (ARDS) using a murine model, finding that increased iRBC cytoadherence and inflammation contribute to ARDS pathogenesis.
bioRxiv · Oct 16, 2019Pathology