A novel splice variant of human TGF-β type II receptor encodes a soluble protein and its Fc-tagged version prevents liver fibrosis in vivo.
M. S. Bertolio, A. La Colla, A. Carrea, A. Romo, G. Canziani, S. M. Echarte, S. Campisano, G. P. Barletta, A. M. Monzon, T. M. Rodriguez, A. N. Chisari, R. A. Dewey
The paper identifies a novel splice variant of the TGF-β type II receptor that acts as a soluble protein and shows protective effects against liver fibrosis in vivo.
bioRxiv · Mar 1, 2021Cell Biology