Formin tails act as a switch, inhibiting or enhancing processive actin elongation
K. Bremer, C. Wu, A. Patel, K. He, A. Grunfeld, G. Chanfreau, M. E. Quinlan
The paper investigates how tail domains in formins regulate actin assembly through alternative splicing, showing that some tails inhibit processive elongation while others enhance it.
bioRxiv · Sep 6, 2023Biochemistry