GAGA zinc finger transcription factor searches chromatin by 1D-3D facilitated diffusion
X. A. Feng, M. Yamadi, Y. Fu, K. M. Ness, C. Liu, I. Ahmed, G. D. Bowman, M. E. Johnson, T. Ha, C. Wu
This study tracks GAF's chromatin search mechanism using smFRET and imaging, showing 1D-3D diffusion enables efficient target finding despite nucleosome barriers.
bioRxiv · Jul 14, 2023Biophysics