Cytotrophoblast cells are selectively permissive and favor Zika virus, but no other related flavivirus, invasion to the placental stroma
M. I. Viettri, G. I. Caraballo, M. E. Sanchez, A. Espejel-Nunez, A. Betanzos, V. Ortiz-Navarrete, G. Estrada, P. Nava, J. E. Ludert
This study compares Zika virus, Dengue virus, and Yellow Fever vaccine efficiency in infecting cytotrophoblast cells and macrophages, finding ZIKV is more efficient and activates mTOR pathways more strongly.
bioRxiv · Jan 20, 2023 · PreprintMicrobiology