Temporal Changes Guided by Mesenchymal Stem Cells on a 3D Microgel Platform Enhances Angiogenesis In Vivo at a Low-Cell Dose
D. Thomas, G. Marsico, I. L. Mohd Isa, A. Thirumaran, X. Chen, B. Lukasz, G. Fontana, B. Rodriguez, M. Marchetti-Deschmann, T. O'Brien, A. Pandit
This study shows that preconditioning mesenchymal stem cells on a 3D microgel platform enhances angiogenesis in vivo at a low-cell dose by modulating extracellular stiffness and integrin signaling.
bioRxiv · May 16, 2020Bioengineering