Author

G. Hoefner

Primary ORCID profile (0000-0002-7957-4503 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

G. HOEFNERiD1 paper · Ludwig-Maximilians-Universität München

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:rat· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

C. G. W. Gertzen· 2 shared D. Steinritz· 2 shared F. F. Paintner· 2 shared F. Worek· 2 shared H. Gohlke· 2 shared J. Kaiser· 2 shared K. T. Wanner· 2 shared K. V. Niessen· 2 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPharmacology & Toxicology

C. G. W. Gertzen

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2 papers

Recent·Most cited

Synthesis and Biological Evaluation of Novel MB327 Analogs as Resensitizers for Desensitized Nicotinic Acetylcholine Receptors after Intoxication with Nerve Agents

T. Bernauer, V. Nitsche, J. Kaiser, C. G. W. Gertzen, G. Hoefner, K. V. Niessen, T. Seeger, D. Steinritz, F. Worek, H. Gohlke, K. T. Wanner, F. F. Paintner

This study synthesizes and evaluates new MB327 analogs as resensitizers for desensitized nicotinic acetylcholine receptors after nerve agent intoxication, identifying more potent compounds than MB327.

bioRxiv · Feb 9, 2024Pharmacology & Toxicology

MS Binding Assays with UNC0642 as reporter ligand for the MB327 binding site of the nicotinic acetylcholine receptor

V. Nitsche, G. Hoefner, J. Kaiser, C. G. W. Gertzen, T. Seeger, K. V. Niessen, D. Steinritz, F. Worek, H. Gohlke, F. F. Paintner, K. T. Wanner

The paper establishes MS Binding Assays using UNC0642 as a reporter ligand to study the MB327 binding site of the nicotinic acetylcholine receptor, showing its effectiveness in both in vitro and in silico studies.

bioRxiv · Nov 15, 2023Pharmacology & Toxicology