The structural basis for release factor activation during translation termination revealed by time-resolved cryogenic electron microscopy
Z. Fu, G. Indrisiunaite, S. Kaledhonkar, B. Shah, M. Sun, B. Chen, R. A. Grassucci, M. Ehrenberg, J. Frank
This paper uses time-resolved cryo-EM to directly observe the transition of bacterial release factors RF1 and RF2 from a compact to extended conformation during translation termination.
bioRxiv · Nov 14, 2018Biophysics