Performance of novel antibodies for lipoarabinomannan to develop diagnostic tests for Mycobacterium tuberculosis
J. L. Cantera, L. M. Lillis, R. B. Peck, E. Moreau, J. A. Schouten, P. Davis, P. K. Drain, A. Andama, A. Pinter, M. Kawasaki, G. Kallenius, C. Sundling, K. M. Dobos, D. Flores, D. Chatterjee, , D. S. Boyle
This study evaluates new LAM-specific antibodies for TB diagnosis, finding that while some show strong binding to cultured LAM, their performance with urinary LAM varies, and no new antibodies outperform existing ones in clinical samples.
bioRxiv · Apr 12, 2022Microbiology