Author

D. Flores

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Organism:mouse· 2 Assay:proteomics· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Andama· 1 shared A. Cupic· 1 shared A. Garcia-Sastre· 1 shared A. L. Marciszyn· 1 shared A. Marin· 1 shared A. Pinter· 1 shared A. R. Subramanya· 1 shared A. S. Gonzalez-Reiche· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Andama

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis.

T. Kehrer, A. Cupic, C. Ye, S. Yildiz, M. Bouhhadou, N. A. Crossland, E. Barrall, P. Cohen, A. Tseng, T. Cagatay, R. Rathnasinghe, D. Flores, S. Jangra, F. Alam, N. Mena, , L. Miorin

This study shows SARS-CoV-2 ORF6 disrupts nucleo-cytoplasmic trafficking, inhibits IFN signaling, and modulates viral protein expression, with variant polymorphisms affecting its function.

bioRxiv · Oct 18, 2022Microbiology

Performance of novel antibodies for lipoarabinomannan to develop diagnostic tests for Mycobacterium tuberculosis

J. L. Cantera, L. M. Lillis, R. B. Peck, E. Moreau, J. A. Schouten, P. Davis, P. K. Drain, A. Andama, A. Pinter, M. Kawasaki, G. Kallenius, C. Sundling, K. M. Dobos, D. Flores, D. Chatterjee, , D. S. Boyle

This study evaluates new LAM-specific antibodies for TB diagnosis, finding that while some show strong binding to cultured LAM, their performance with urinary LAM varies, and no new antibodies outperform existing ones in clinical samples.

bioRxiv · Apr 12, 2022Microbiology

L-WNK1 is required for BK channel activation in intercalated cells

E. C. Ray, R. Carrisoza, M. Al-Bataineh, A. L. Marciszyn, L. Nkashama, J. C. Chen, A. Winfrey, D. Flores, P. Wu, W. C. Wang, c.-l. wang, A. R. Subramanya, T. R. Kleyman, L. M. Satlin

This study shows that L-WNK1 in intercalated cells enhances BK channel activity in response to a high K+ diet, which is critical for urinary K+ secretion.

bioRxiv · Jan 26, 2021Physiology

Cwl0971, a novel peptidoglycan hydrolase, plays pleiotropic roles in Clostridioides difficile R20291

D. Zhu, H. M. L. W. Patabendige, B. R. Tomlinson, S. Wang, D. Flores, Y. He, L. Shaw, X. Sun

This study identifies Cwl0971 as a peptidoglycan hydrolase in C. difficile that affects autolysis, toxin release, sporulation, and pathogenicity.

bioRxiv · Nov 29, 2020Microbiology