Author

G. L. Chadwick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:metagenomics· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Approach:comparative / phylogenetic analysis· 1 Approach:deep learning· 1

Frequent Co-Authors

D. D. Nayak· 2 shared H. Yu· 2 shared W. J. Brazelton· 2 shared A. A. Garcia· 1 shared A. Boetius· 1 shared A. M. Hoffman· 1 shared A. M. Joiner· 1 shared A. O. Leu· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersMicrobiology

D. D. Nayak

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Physiological and transcriptomic response to methyl-coenzyme M reductase limitation in Methanosarcina acetivorans

D. D. Nayak, G. L. Chadwick, G. A. Dury

This study investigates the physiological and transcriptomic response of Methanosarcina acetivorans to MCR limitation, showing that MCR is not growth rate limiting in substrate-replete cultures but can become limiting under specific conditions.

bioRxiv · Dec 13, 2023 · PreprintMicrobiology

Discovery of two archaeal GDGT lipid modifying enzymes reveals diverse microbes capable of H-GDGT biosynthesis and modification

A. A. Garcia, G. L. Chadwick, P. V. Welander

This paper identifies two archaeal enzymes involved in H-GDGT lipid modifications and demonstrates their role in producing diverse H-GDGT structures under different environmental conditions.

bioRxiv · Oct 20, 2023Microbiology

McrD binds asymmetrically to methyl-coenzyme M reductase improving active site accessibility during assembly

G. L. Chadwick, A. M. Joiner, S. Ramesh, D. A. Mitchell, D. D. Nayak

The paper structurally characterizes intermediate states of methyl-coenzyme M reductase (MCR) assembly, revealing McrD's role in facilitating F430 cofactor installation.

bioRxiv · Feb 1, 2023Biochemistry

Metabolic strategies shared by basement residents of the Lost City hydrothermal field

W. J. Brazelton, J. M. McGonigle, S. Motamedi, H. L. Pendleton, K. I. Twing, B. C. Miller, W. J. Lowe, A. M. Hoffman, C. A. Prator, G. L. Chadwick, R. E. Anderson, E. Thomas, D. A. Butterfield, K. A. Aquino, G. L. Früh-Green, , S. Q. Lang

This study identifies key microbial species and metabolic strategies in hydrothermal fluids from the Lost City field, revealing adaptations to geochemically driven energy sources.

bioRxiv · Jan 25, 2022Microbiology

Comparative genomics on cultivated and uncultivated, freshwater and marine Candidatus Manganitrophaceae species implies their worldwide reach in manganese chemolithoautotrophy

H. Yu, G. L. Chadwick, U. F. Lingappa, J. R. Leadbetter

The paper identifies a new bacterial family, Candidatus Manganitrophaceae, capable of manganese-dependent chemolithoautotrophy, found globally in freshwater and marine environments.

bioRxiv · Nov 15, 2021Microbiology

Comparative genomics reveals electron transfer and syntrophic mechanisms differentiating methanotrophic and methanogenic archaea

G. L. Chadwick, C. T. Skennerton, R. Laso-Perez, A. O. Leu, D. R. Speth, H. Yu, C. Morgan-Lang, R. Hatzenpichler, D. Goudeau, R. Malmstrom, W. J. Brazelton, T. Woyke, S. J. Hallam, G. W. Tyson, G. Wegener, , V. J. Orphan

The paper compares genomes of methanotrophic and methanogenic archaea to identify differences in electron transfer and metabolic pathways.

bioRxiv · Sep 25, 2021Microbiology