A novel patient-derived cellular platform for validating microglia-targeted therapeutics for Alzheimer's disease
C. Cuni-Lopez, R. Stewart, S. Okano, G. L. Redlich, M. W. Appleby, A. R. White, H. Quek
This study develops a patient-derived cellular platform to test microglia-targeted therapeutics for Alzheimer's disease, finding that 3D models better distinguish drug responses between healthy and patient donors.
bioRxiv · Aug 17, 2023 · PreprintCell Biology