Molecular dissection of PI3Kβ synergistic activation by receptor tyrosine kinases, GβGγ, and Rho-family GTPases
B. R. Duewell, N. E. Wilson, G. M. Bailey, S. E. Peabody, S. D. Hansen
This study investigates how PI3Kβ integrates signals from RTKs, Gβγ, and Rho-family GTPases, revealing synergistic activation through allosteric regulation.
bioRxiv · May 1, 2023Biochemistry