Development of a SARS-COV-2 monoclonal antibody panel and its applicability as a reagent in high-throughput fluorescence reduction neutralization and immunohistochemistry assays
G. Mattoso, A. Cataneo, S. M. Raboni, M. B. Nogueira, C. Vaz de Paula, A. C. Almeida, V. Rogerio, N. Zanchin, L. de Noronha, C. Zanluca, C. N. Duarte dos Santos
This study develops a high-throughput fluorescence reduction neutralization assay (FRNA) using monoclonal antibodies to measure SARS-CoV-2 neutralizing antibodies, showing strong correlation with standard PRNT while reducing time by 70%.
bioRxiv · May 29, 2023 · PreprintMicrobiology