Exposure to hypomethylating agent 5-aza-2-deoxycytidine (decitabine) causes rapid, severe DNA damage, telomere elongation and mitotic dysfunction in human WIL2-NS cells
C. Bull, G. Mayrhofer, M. Fenech
This study shows that 5-aza-2-deoxycytidine causes DNA damage, telomere elongation, and mitotic dysfunction in human WIL2-NS cells at clinically relevant doses.
bioRxiv · Nov 7, 2019Cancer Biology