Respiratory depression and analgesia by opioid drugs in freely-behaving larval zebrafish
S. Zaig, C. da Silveira Scarpellini, G. Montandon
This study shows that fentanyl induces respiratory depression and analgesia in larval zebrafish, effects reversed by mu-opioid receptor antagonists, suggesting conserved opioid mechanisms across species.
bioRxiv · Sep 30, 2020Physiology