Network inference at single-cell resolution reveals morphoregulatory divergence and multilayered buffering in limb evolution
A. Alcaina-Caro, I. Sospedra-Arrufat, V. Tissieres, I. Salvador-Martinez, L. Almorox, J. J. Pawluk, A. Diaz-Rueda, A. Fernandez-Minan, A. Hurtado, F. Martinez Real, D. Lupianez, B. Pernaute, A. Visel, M. Osterwalder, H. Heyn, , Javier Lopez-Rios
The paper compares gene regulatory networks in mouse and pig limb development to reveal conserved and divergent regulatory programs and mechanisms of developmental robustness.
bioRxiv · Nov 9, 2026 · PreprintDevelopmental Biology