J. J. Tena

Chromosome-level genome assemblies of two hemichordates provide new insights into deuterostome origin and chromosome evolution

This study presents chromosome-level genome assemblies of two hemichordates to infer deuterostome ancestral chromosomal architecture and lineage-specific modifications.

An amphioxus neurula stage cell atlas supports a complex scenario for the emergence of vertebrate head mesoderm

The paper constructs a single-cell RNA-seq atlas of amphioxus neurula stage to investigate the evolutionary origins of vertebrate head mesoderm.

The cellular landscape of the endochondral bone during the transition to extrauterine life

This study profiles the single-cell composition of murine endochondral bone during the perinatal transition, identifying fibroblastic clusters and dynamic interactions relevant to skeletogenesis and immune development.

Insights into deuterostome evolution from the biphasic transcriptional programmes of hemichordates

This study identifies a biphasic developmental program in hemichordates, revealing conserved gene regulatory networks and cis-regulatory elements across deuterostomes.

The little skate genome and the evolutionary emergence of wing-like fin appendages

This study identifies genomic rearrangements and regulatory changes in the little skate that contribute to the evolution of wing-like fin appendages.

Parallel evolution of amphioxus and vertebrate small-scale gene duplications

This study compares small-scale gene duplication patterns between amphioxus and vertebrates, finding similar duplication histories and functional constraints despite amphioxus' slower evolution.

Gain of gene regulatory network interconnectivity at the origin of vertebrates

The paper shows that increased interconnectivity between signaling pathways and gene regulatory networks contributed to vertebrate evolution by enabling new gene expression patterns and cell types.

Ancient genomic regulatory blocks are a major source for gene deserts in vertebrates after whole genome duplications

The paper shows that ancient genomic regulatory blocks (GRBs) were maintained as single copies in humans after vertebrate whole genome duplications, with their duplicated copies dismantled to form gene deserts.