Fonsecaea pedrosoi conidia and hyphae activate neutrophils distinctly: Requirement of TLR-2 and TLR-4 in neutrophil effector functions
L. C. D. Breda, C. N. d. S. Breda, J. R. F. de Almeida, L. N. M. Paulo, G. P. Jannuzzi, I. d. G. Menezes, R. C. Albuquerque, N. O. S. Camara, K. S. Ferreira, S. R. Almeida
This study shows that neutrophils kill Fonsecaea pedrosoi conidia and hyphae through distinct mechanisms, with TLR-2 and TLR-4 required for conidial killing but not hyphal killing.
bioRxiv · Jan 6, 2020Immunology