Integrated RNA and metabolite profiling of urine liquid biopsies for prostate cancer biomarker discovery
B. Lee, I. Mahmud, J. Marchica, P. Derezinski, F. Qi, F. Wang, P. Joshi, F. Valerio, I. Rivera, V. Patel, C. P. Pavlovich, T. Garrett, G. P. Schroth, Y. Sun, R. J. Perera
The paper identifies urine-enriched RNAs and metabolites in prostate cancer patients and normal individuals, revealing altered glutamate metabolism and TCA cycle in cancer cells.
bioRxiv · Apr 4, 2019Cancer Biology