Author

R. J. Perera

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 5

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 5 Organism:human· 5 Research Focus:differential expression· 4 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

B. Lee· 4 shared P. Joshi· 4 shared J. Marchica· 2 shared A. Bergano· 1 shared A. Garancher· 1 shared A. Ray· 1 shared A. Sahoo· 1 shared B. Liu· 1 shared

Activity by Year

2019-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersCancer Biology

B. Lee

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5 papers

Recent·Most cited

The long non-coding RNA lnc-HLX-2-7 is oncogenic in group 3 medulloblastomas

K. Katsushima, B. Lee, H. Kunhiraman, C. Zhong, R. Murath, J. Ying, B. Liu, A. Garancher, H. L. Monforte, I. Gonzalez-Gomez, S. Stapleton, R. Vibhakar, C. Bettegowda, R. J. Wechsler-Reya, G. Jallo, , R. J. Perera

This study identifies lnc-HLX-2-7 as an oncogenic lncRNA in group 3 medulloblastomas, showing it promotes tumor growth and is regulated by MYC and JQ1.

bioRxiv · Jun 8, 2020Cancer Biology

In silico analysis of long non-coding RNAs in medulloblastoma and its subgroups

P. Joshi, R. J. Perera

The paper performs an in silico analysis of long non-coding RNAs in medulloblastoma, identifying subgroup-specific lncRNAs and developing diagnostic and prognostic models.

bioRxiv · Mar 3, 2020Cancer Biology

Transcriptome stability profiling identifies novel and functional MIRNA targets in melanoma cells

P. Joshi, T. Seki, S. Kitamura, A. Bergano, B. Lee, R. J. Perera

The paper uses RNA stability profiling to identify novel miR-211 targets in melanoma cells and validates their functional role in cell invasion and colony formation.

bioRxiv · Jun 1, 2019Cancer Biology

Integrated RNA and metabolite profiling of urine liquid biopsies for prostate cancer biomarker discovery

B. Lee, I. Mahmud, J. Marchica, P. Derezinski, F. Qi, F. Wang, P. Joshi, F. Valerio, I. Rivera, V. Patel, C. P. Pavlovich, T. Garrett, G. P. Schroth, Y. Sun, R. J. Perera

The paper identifies urine-enriched RNAs and metabolites in prostate cancer patients and normal individuals, revealing altered glutamate metabolism and TCA cycle in cancer cells.

bioRxiv · Apr 4, 2019Cancer Biology

Exosome-mediated MIR211 modulates tumor microenvironment via the DUSP6-ERK5 axis and contributes to BRAFV600E inhibitor resistance in melanoma.

B. Lee, A. Sahoo, J. Marchica, J. Sawada, S. Sahoo, F. I. A. L. Layng, D. Finlay, J. Mazar, P. Joshi, M. Komatsu, K. Vuori, G. Powis, P. R. de Jong, A. Ray, R. J. Perera

This study shows MIR211 promotes melanoma growth and resistance to BRAF inhibitors by modulating the DUSP6-ERK5 axis via exosome transfer in the tumor microenvironment.

bioRxiv · Feb 13, 2019 · PreprintCancer Biology