A hybrid structure determination approach to investigate the druggability of the nucleocapsid protein of SARS-CoV-2
G. Padroni, M. Bikaki, M. Novakovic, A. C. Wolter, S. H. Ruedisser, A. D. Gossert, A. Leitner, F. H.- T. Allain
The paper develops a hybrid method combining NMR and mass spectrometry to study RNA binding and druggability of SARS-CoV-2 N-protein, identifying potential drug candidates.
bioRxiv · Sep 15, 2022Biophysics