A Locally Activatable Sensor for Robust Quantification of Organellar Glutathione
S. Hübner, G. Quargnali, S. Thallmair, P. Rivera-Fuentes
The paper introduces TRaQ-G, a sensor for live-cell imaging of organellar glutathione, showing independent regulation of nuclear and cytosolic GSH during cell proliferation and simultaneous redox potential quantification in the endoplasmic reticulum.
bioRxiv · Apr 1, 2022Cell Biology