BiophysicsbioRxivPreprint
N-terminal mutants of human apolipoprotein A-I: structural perturbations associated to protein misfolding
G. M. Gaddi, R. A. Gisonno, S. A. Rosu…·M. A. Tricerri
This study investigates how the L60R mutation in apolipoprotein A-I causes structural instability and misfolding, leading to protein aggregation and inflammatory responses.
DOI 10.1101/520171