Loss of calpain 3 dysregulates store-operated calcium entry and its exercise response in mice
K. R. Villani, R. Zhong, C. S. Henley-Beasley, G. Rastelli, S. Boncompagni, E. R. Barton, L. Wei-LaPierre
This study shows that loss of Calpain 3 in mice disrupts Store-Operated Calcium Entry (SOCE) and its response to exercise, contributing to LGMD2A pathology.
bioRxiv · Jan 12, 2024Physiology