New tools for automated cryo-EM single-particle analysis in RELION-4.0
D. Kimanius, L. Dong, G. Sharov, T. Nakane, S. H. W. Scheres
The paper introduces new tools in RELION-4.0 for automated cryo-EM single-particle analysis, including a gradient descent algorithm, a neural network for 2D class selection, and a job framework with metadata linking.
bioRxiv · Sep 30, 2021Biophysics