Author

G. Stolovitzky

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Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Califano· 1 shared B. Losic· 1 shared C. Karan· 1 shared J. E. L. Diaz· 1 shared M. E. Ahsen· 1 shared R. B. Realubit· 1 shared T. Schaffter· 1 shared X. Chen· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperCell Biology

A. Califano

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1 paper

Recent·Most cited

The transcriptomic response of cells to a drug combination is more than the sum of the responses to the monotherapies

J. E. L. Diaz, M. E. Ahsen, T. Schaffter, X. Chen, R. B. Realubit, C. Karan, A. Califano, B. Losic, G. Stolovitzky

The paper shows that drug combination transcriptional responses are not simply additive and develops a prediction algorithm with 0.84 AUROC for synergistic combinations.

bioRxiv · Nov 18, 2019Cell Biology