The Antagonism of Folate Receptor by the Integrase Inhibitor Dolutegravir
R. M. Cabrera, J. P. Souder, J. W. Steele, L. Yeo, G. Tukeman, D. A. Gorelick, R. H. Finnell
This study investigates how dolutegravir antagonizes folate receptor 1 and its developmental toxicity in zebrafish, showing folic acid can mitigate its effects.
bioRxiv · Mar 14, 2019 · PreprintPharmacology & Toxicology