Super-Resolution Imaging Uncovers Nanoscale Tau Aggregate Hyperphosphorylation Patterns in Human Alzheimers Disease Brain Tissue
Adriana N. Santiago-Ruiz, Siewert Hugelier, Gabriela L. Correa, Charles Bond, Edward B. Lee, Melike Lakadamyali
The paper uses super-resolution imaging to analyze nanoscale tau aggregates in AD and PART brain tissues, revealing hyperphosphorylation patterns and morphological differences.
Advanced Science · Nov 19, 2025Peer-reviewedBiophysics