A high-fat high-sugar diet in adolescent rats impairs social memory and alters chemical markers characteristic of atypical neuroplasticity and GABAergic neurodevelopment in the medial prefrontal cortex
Amy Claire Reichelt, Gabrielle D. Gibson, Kirsten N. Abbott, Dominic James Hare
This study shows that a high-fat high-sugar diet in adolescent rats reduces PV+ neurons and PNNs in the infralimbic region and increases co-expression of PV+ and PNNs in mPFC regions, associated with social memory deficits.
Food & Function · Jan 1, 2019Peer-reviewedNeuroscience