Dominic James Hare

Disrupted copper availability in sporadic ALS: Implications for CuII(atsm) as a treatment option

The paper investigates copper availability in sporadic ALS and suggests CuII(atsm) may be therapeutically relevant by improving copper bioavailability.

Microglial ferroptotic stress causes non-cell autonomous neuronal death

This study shows that microglial ferroptotic stress leads to non-cell autonomous neuronal death in ALS, with a novel inhibitor reducing neurotoxicity.

A high-fat high-sugar diet in adolescent rats impairs social memory and alters chemical markers characteristic of atypical neuroplasticity and GABAergic neurodevelopment in the medial prefrontal cortex

This study shows that a high-fat high-sugar diet in adolescent rats reduces PV+ neurons and PNNs in the infralimbic region and increases co-expression of PV+ and PNNs in mPFC regions, associated with social memory deficits.