Meta-analysis and multi-omics to elucidate pathogenic mechanisms of age-related knee osteoarthritis
Hirotaka Iijima, Gabrielle Gilmer, Kai Wang, Sruthi Sivakumar, Christopher H. Evans, Yusuke Matsui, Fabrisia Ambrosio
This study uses meta-analysis and multi-omics to identify inflammation, autophagy, and cellular senescence as key features of age-related KOA in mice, with unique molecular profiles distinct from post-traumatic OA.
The Journals of Gerontology Series A · Jan 3, 2022Peer-reviewedMolecular Biology