Genome-scale spatial mapping of the Hodgkin lymphoma microenvironment identifies tumor cell survival factors
Vignesh Shanmugam, Neriman Tokcan, Daniel Chafamo, Sean Sullivan, Mehdi Borji, Haley K. Martin, Gail A. Newton, Naeem M. Nadaf, Saoirse Hanbury, Irving Barrera, Dylan M. Cable, Jackson A. Weir, Orr Ashenberg, Geraldine Pinkus, Scott J. Rodig, , Todd R. Golub
This study identifies IL13 as a survival factor for Hodgkin lymphoma cells by analyzing the tumor microenvironment with spatial and single-cell resolution.
Nature Communications · Dec 20, 2025Peer-reviewedCancer Biology