Mehdi Borji

This study identifies IL13 as a survival factor for Hodgkin lymphoma cells by analyzing the tumor microenvironment with spatial and single-cell resolution.

The paper introduces SPICE, a framework that uses splicing assays and generative design to create cell-specific gene regulation elements for research and therapy.

The paper analyzes single-cell data from bone marrow samples to identify immune cell interactions that predict response to adoptive cellular therapy in myeloid leukemia.

The paper develops a tool for continuous, long-range, targeted diversification of endogenous mammalian genomes and uses it to explore the function of genetic variants in both coding and non-coding regions.

This paper introduces an imaging-free spatial transcriptomics method using molecular diffusion patterns and UMAP to reconstruct spatial data with high fidelity and scalability.