CRISPys: Optimal sgRNA design for editing multiple members of a gene family using the CRISPR system
Gal Hyams, Shiran Abadi, Shlomtzion Lahav, Adi Avni, Eran Halperin, Eilon Shani, Itay Mayrose
CRISPys is an algorithm for designing CRISPR sgRNAs that target multiple gene family members by leveraging the system's reduced specificity to simultaneously knockout homologous genes.
Journal of Molecular Biology · Apr 3, 2018Peer-reviewedBioinformatics