Author

Shlomtzion Lahav

Hebrew University of Jerusalem

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:statistical model· 3 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:CRISPR screen· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Adi Alajem· 2 shared Danny Bavli· 2 shared Oren RamiD· 2 shared Adi AvniiD· 1 shared Alex Motzik· 1 shared Eilon ShaniiD· 1 shared Eran HalperiniD· 1 shared Gal Hyams· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMolecular Biology

Adi Alajem

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3 papers

Recent·Most cited

DNA Methylation Patterns Expose Variations in Enhancer-Chromatin Modifications during Embryonic Stem Cell Differentiation

Adi Alajem, Hava Roth, Sofia Ratgauzer, Danny Bavli, Alex Motzik, Shlomtzion Lahav, Itay Peled, Oren Ram

The paper identifies enhancer-specific DNA methylation variations during mouse embryonic stem cell differentiation using combined histone mark and methylation analysis.

PLoS Genetics · Apr 12, 2021Peer-reviewedMolecular Biology

Esrrb is a cell cycle dependent priming factor balancing between pluripotency and differentiation

Sapir Herchcovici Levy, Sharon Feldman, Lee Arnon, Shlomtzion Lahav, Muhammad Awawdy, Adi Alajem, Danny Bavli, Xue Sun, Yosef Buganim, Oren Ram

This study shows Esrrb promotes XEN differentiation in G2/M phase ESCs and is required for XEN differentiation potential, while its absence leads to loss of differentiation capacity.

bioRxiv · Aug 3, 2020 · PreprintMolecular Biology

CRISPys: Optimal sgRNA design for editing multiple members of a gene family using the CRISPR system

Gal Hyams, Shiran Abadi, Shlomtzion Lahav, Adi Avni, Eran Halperin, Eilon Shani, Itay Mayrose

CRISPys is an algorithm for designing CRISPR sgRNAs that target multiple gene family members by leveraging the system's reduced specificity to simultaneously knockout homologous genes.

Journal of Molecular Biology · Apr 3, 2018Peer-reviewedBioinformatics