Author

Shiran Abadi

Tel Aviv UniversityORCID 0000-0002-3932-6310Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:graph neural network· 1 Organism:human· 1 Research Focus:software / tool· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Adi AvniiD· 1 shared Daniel OffeniD· 1 shared Eilon ShaniiD· 1 shared Eran HalperiniD· 1 shared Gal Hyams· 1 shared Itay MayroseiD· 1 shared Roy RabinowitziD· 1 shared Shiri Almog· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 18 mutual co-author links

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1 shared paperBioinformatics

Adi AvniORCID

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2 papers

Recent·Most cited

Prediction of synonymous corrections by the BE-FF computational tool expands the targeting scope of base editing

Roy Rabinowitz, Shiran Abadi, Shiri Almog, Daniel Offen

BE-FF identifies suitable base editors to correct single nucleotide variations, enabling synonymous corrections for 19.4% of transition mutations and 298 transversion cases.

Nucleic Acids Research · Mar 24, 2020Peer-reviewedBioinformatics

CRISPys: Optimal sgRNA design for editing multiple members of a gene family using the CRISPR system

Gal Hyams, Shiran Abadi, Shlomtzion Lahav, Adi Avni, Eran Halperin, Eilon Shani, Itay Mayrose

CRISPys is an algorithm for designing CRISPR sgRNAs that target multiple gene family members by leveraging the system's reduced specificity to simultaneously knockout homologous genes.

Journal of Molecular Biology · Apr 3, 2018Peer-reviewedBioinformatics