Investigating antiviral pathways in Atlantic salmon cells through interferon receptor knockouts via CRISPR-Cas9
Mohammad Ali Noman Reza, Thomas Nelson Harvey, Amr Ahmed Abdelrahim Gamil, Øystein Evensen, Gareth Benjamin Gillard, Guro Katrine Sandvik
This study uses CRISPR-Cas9 to knockout IFN receptor genes in Atlantic salmon cells to assess their role in antiviral signaling against ISAV and IPNV, revealing gene-specific effects and alternative pathways.
bioRxiv · Jan 14, 2025 · PreprintImmunology