Single cell transcriptomics reveals the effect of PD-L1/TGF-β blockade on the tumor microenvironment
Yoong Wearn Lim, Garry L. Coles, Savreet K. Sandhu, David S. Johnson, Adam S. Adler, Erica Lyn Stone
The paper uses single-cell RNA sequencing to study how PD-L1 and TGF-β blockade affect the tumor microenvironment, finding upregulated immune response genes and downregulated extracellular matrix genes.
BMC Biology · May 24, 2021Peer-reviewedGenomics