SARM1 is required for macrophage immunophenotype switching that is essential for nerve repair
Julianna Bennett, Halimah Adesunkanmi, Noah Leever, Grace Bergeron, Josh Small, C. S. Holladay, Grace Saxman, Rachel E. Williamson, Manshi Swain, Gavin Pearson, Manav Patel, Ashley L. Kalinski
This study shows that SARM1 in macrophages is essential for immunophenotype switching during nerve repair, affecting inflammation, degeneration, and axon regeneration.
bioRxiv · Apr 9, 2026 · PreprintNeuroscience