LIS1 is critical for axon integrity in adult mice
Samaneh Matoo, Anne Ventrone, Shreena Patel, Jack K Otterson, Sean Noonan, Noah Leever, Timothy J. Hines, Ashley L. Kalinski, Deanna S. Smith
This study shows LIS1 depletion in adult mice causes axonal degeneration in projection neurons, suggesting LIS1's role in maintaining axon integrity in mature neurons.
Journal of Neuroscience · Apr 17, 2026Peer-reviewedNeuroscience