Disruption of mitochondrial integrity impairs early lineage specification and embryonic development in the novel conditional MitoAtDarT mouse model
Mona Ahmed, Niyati Gadepalli, Gayathri PS, Maroof Hashmi, Anjana Badrinarayanan, Raj K. Ladher
This study shows that mitochondrial dysfunction in a novel mouse model impairs early lineage specification and embryonic development, highlighting mitochondrial roles in developmental transitions.
bioRxiv · Jul 14, 2025 · PreprintDevelopmental Biology