Genomic and functional adaptations in guanylate-binding protein 5 (GBP5) highlight specificities of bat antiviral innate immunity
Amandine Le Corf, Sarah Maesen, Amandine Chantharath, Clara Loyer, Juan Manuel Vázquez, M. Elise Lauterbur, Veronika Krchlíková, Lucas Sareoua, Genavieve Gray-Sandoval, Andrea Cimarelli, Carine Rey, Peter H. Sudmant, David Enard, Lucie Etienne
This study identifies GBP5 as a key antiviral gene in bats, showing its evolutionary adaptations and functional specificity in restricting viral infections.
PLoS Biology · Apr 21, 2026Peer-reviewedImmunology