Interactions between helicase and primase are crucial for DNA replication in the enteropathogen Clostridium difficile
Erika Van Eijk, Vasileios Paschalis, Matthew Green, Annemieke H. Friggen, Marilynn A. Larson, Keith Spriggs, Geoffrey Briggs, Panos Soultanas, Wiep Klaas Smits
This study identifies and characterizes the DNA replication machinery of Clostridium difficile, showing that helicase-primase interactions are essential for DNA replication initiation.
bioRxiv · Aug 29, 2016Microbiology