IL-4 shaping glutamatergic synapse like structures for more mature iPSC derived neuron phenotypes
David Zimmermann, Clemens L. Schöpf, Georg Kern, Theodora Kalpachidou, Maximilian Zeidler, Michaela Kress
This study shows IL-4 promotes synapse formation in iPSC-derived neurons by activating specific signaling pathways and inducing transcriptomic changes related to neuronal development and regeneration.
bioRxiv · Dec 5, 2023 · PreprintNeuroscience