Fine needle aspiration biopsy of breast specimens effectively harvests cells for patient-derived organoids modeling breast ductal carcinoma in situ
Julia Ye, Nadine Goldhammer, Poonam Vohra, Shruti Warhadpande, George C. De Castro, Cristian K. Maldonado Rodas, Mark M. Moasser, Kirithiga Ramalingam, Shoko Emily Abe, Michael D Alvarado, Cheryl Ann Ewing, Karen J Goodwin, Rita A. Mukhtar, Jasmine Wong, Laura J. Esserman, , Jennifer M. Rosenbluth
This study shows that fine needle aspiration biopsy (FNAB) effectively harvests cells for patient-derived organoids modeling breast ductal carcinoma in situ, with faster growth times compared to core needle biopsy.
bioRxiv · Aug 12, 2025 · PreprintCell Biology