Allele-specific DNA methylation is increased in cancers and its dense mapping in normal plus neoplastic cells increases the yield of disease-associated regulatory SNPs
Catherine Do, Emmanuel LP Dumont, Martha C. Salas, Angelica M. Castano, Huthayfa Mujahed, Leonel Maldonado, Arunjot Singh, Sonia C. DaSilva‐Arnold, Govind Bhagat, Soren Lehman, Angela M. Christiano, Subha Madhavan, Péter L. Nagy, Peter H.R. Green, Rena Feinman, , Benjamin Tycko
The paper maps allele-specific DNA methylation in normal and cancer tissues, identifying disease-associated regulatory SNPs that are missed by other methods.
Genome biology · Jun 28, 2020Peer-reviewedGenomics