Emmanuel LP Dumont

Genetic Ethnicity and Hypertension Epistatic Interaction Underlying Racial Disparities in US Multiple Myeloma Susceptibility

The paper identifies an epistatic interaction between genetic ethnicity and hypertension that explains racial disparities in multiple myeloma risk among Black and mixed-ancestry individuals.

Improving allele-specific epigenomic signal coverage by 10-fold using Hidden Markov Modeling and Machine Learning

This paper improves allele-specific epigenomic signal coverage by 10-fold using variational hidden Markov modeling and machine learning, demonstrating it on DNA methylation data.

Allele-specific DNA methylation is increased in cancers and its dense mapping in normal plus neoplastic cells increases the yield of disease-associated regulatory SNPs

The paper maps allele-specific DNA methylation in normal and cancer tissues, identifying disease-associated regulatory SNPs that are missed by other methods.

CloudASM: an ultra-efficient cloud-based pipeline for mapping allele-specific DNA methylation

CloudASM provides an efficient cloud-based pipeline for quantifying allele-specific DNA methylation by leveraging Google Cloud Computing infrastructure.