In vitro model of inflammatory, hypoxia, and cancer stem cell signaling in pancreatic cancer using heterocellular 3-dimensional spheroids
Megha Suresh, George Mattheolabakis, Amit Singh, Mansoor Amiji
This study develops 3D co-culture spheroid models of pancreatic cancer to mimic tumor microenvironment interactions and assess inflammatory, hypoxia, and cancer stem cell markers.
bioRxiv · Oct 26, 2018 · PreprintCancer Biology