Enhanced C/EBPα function extends healthspan and lifespan in the African turquoise killifish
Christine Müller, Joscha Sergej Muck, Kirill Ustyantsev, Gertrud Kortman, Josephine Hartung, Eugène Berezikov, Cornelis F. Calkhoven
This study shows that disrupting a regulatory element in the CEBPA gene of African turquoise killifish increases lifespan and healthspan by enhancing full-length C/EBP isoform activity.
Aging Cell · Sep 19, 2025Peer-reviewedPhysiology